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Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions

BACKGROUND: It has become evident that host cells react to recombinant protein production with a variety of metabolic and intrinsic stresses such as the unfolded protein response (UPR) pathway. Additionally, environmental conditions such as growth temperature may have a strong impact on cell physiol...

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Detalles Bibliográficos
Autores principales:	Gasser, Brigitte, Maurer, Michael, Rautio, Jari, Sauer, Michael, Bhattacharyya, Anamitra, Saloheimo, Markku, Penttilä, Merja, Mattanovich, Diethard
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919374/ https://www.ncbi.nlm.nih.gov/pubmed/17578563 http://dx.doi.org/10.1186/1471-2164-8-179

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