Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics

BACKGROUND: Tests for association between a haplotype and disease are commonly performed using a likelihood ratio test for heterogeneity between case and control haplotype frequencies. Using data from a study of association between heroin dependence and the DRD2 gene, we obtained estimated haplotype...

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Detalles Bibliográficos
Autores principales: Curtis, David, Xu, Ke
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919392/
https://www.ncbi.nlm.nih.gov/pubmed/17597526
http://dx.doi.org/10.1186/1471-2156-8-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919392/
https://www.ncbi.nlm.nih.gov/pubmed/17597526
http://dx.doi.org/10.1186/1471-2156-8-38

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