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Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics
BACKGROUND: Tests for association between a haplotype and disease are commonly performed using a likelihood ratio test for heterogeneity between case and control haplotype frequencies. Using data from a study of association between heroin dependence and the DRD2 gene, we obtained estimated haplotype...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919392/ https://www.ncbi.nlm.nih.gov/pubmed/17597526 http://dx.doi.org/10.1186/1471-2156-8-38 |