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Early Energy Deficit in Huntington Disease: Identification of a Plasma Biomarker Traceable during Disease Progression
Huntington disease (HD) is a fatal neurodegenerative disorder, with no effective treatment. The pathogenic mechanisms underlying HD have not been elucidated, but weight loss, associated with chorea and cognitive decline, is a characteristic feature of the disease that is accessible to investigation....
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919424/ https://www.ncbi.nlm.nih.gov/pubmed/17653274 http://dx.doi.org/10.1371/journal.pone.0000647 |