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Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies

R1Bm is a long interspersed element (LINE) inserted into a specific sequence within 28S rDNA of the silkworm genome. Of two open reading frames (ORFs) of R1Bm, ORF2 encodes a reverse transcriptase (RT) and an endonuclease (EN) domain which digests specifically both top and bottom strand of the targe...

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Detalles Bibliográficos
Autores principales: Maita, Nobuo, Aoyagi, Hideyuki, Osanai, Mizuko, Shirakawa, Masahiro, Fujiwara, Haruhiko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919474/
https://www.ncbi.nlm.nih.gov/pubmed/17537809
http://dx.doi.org/10.1093/nar/gkm397