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Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies
R1Bm is a long interspersed element (LINE) inserted into a specific sequence within 28S rDNA of the silkworm genome. Of two open reading frames (ORFs) of R1Bm, ORF2 encodes a reverse transcriptase (RT) and an endonuclease (EN) domain which digests specifically both top and bottom strand of the targe...
Autores principales: | Maita, Nobuo, Aoyagi, Hideyuki, Osanai, Mizuko, Shirakawa, Masahiro, Fujiwara, Haruhiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919474/ https://www.ncbi.nlm.nih.gov/pubmed/17537809 http://dx.doi.org/10.1093/nar/gkm397 |
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