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Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore
One of the major obstacles in non-viral gene transfer is the nuclear membrane. Attempts to improve the transport of DNA to the nucleus through the use of nuclear localization signals or importin-β have achieved limited success. It has been proposed that the nuclear pore complexes (NPCs) through whic...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919477/ https://www.ncbi.nlm.nih.gov/pubmed/17584788 http://dx.doi.org/10.1093/nar/gkm440 |