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Explaining differences in saturation levels for Affymetrix GeneChip® arrays

The experimental spike-in studies of microarray hybridization conducted by Affymetrix demonstrate a nonlinear response of fluorescence intensity signal to target concentration. Several theoretical models have been put forward to explain these data. It was shown that the Langmuir adsorption isotherm...

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Detalles Bibliográficos
Autores principales: Skvortsov, Dmitriy, Abdueva, Diana, Curtis, Christina, Schaub, Betty, Tavaré, Simon
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919478/
https://www.ncbi.nlm.nih.gov/pubmed/17567617
http://dx.doi.org/10.1093/nar/gkm348