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In vitro selection of a 5′-purine ribonucleotide transferase ribozyme
Here we report in vitro selection of a novel ribozyme that catalyzes the 5′-nucleotidyl transfer reaction forming the 2′–5′ phosphodiester bond. This ribozyme was retrieved as a sole sequence in the pool enriched for the 5′-triphosphate-dependent activities in incorporating ATP-γS. The originally se...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919479/ https://www.ncbi.nlm.nih.gov/pubmed/17567602 http://dx.doi.org/10.1093/nar/gkm438 |