Relative abundance of the human mitochondrial transcription system and distinct roles for h-mtTFB1 and h-mtTFB2 in mitochondrial biogenesis and gene expression

Human mitochondrial transcription requires the bacteriophage-related RNA polymerase, POLRMT, the mtDNA-binding protein, h-mtTFA/TFAM, and two transcription factors/rRNA methyltransferases, h-mtTFB1 and h-mtTFB2. Here, we determined the steady-state levels of these core transcription components and e...

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Detalles Bibliográficos
Autores principales: Cotney, Justin, Wang, Zhibo, Shadel, Gerald S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919481/
https://www.ncbi.nlm.nih.gov/pubmed/17557812
http://dx.doi.org/10.1093/nar/gkm424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919481/
https://www.ncbi.nlm.nih.gov/pubmed/17557812
http://dx.doi.org/10.1093/nar/gkm424

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