Uracil–DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms

DNA glycosylases UNG and SMUG1 excise uracil from DNA and belong to the same protein superfamily. Vertebrates contain both SMUG1 and UNG, but their distinct roles in base excision repair (BER) of deaminated cytosine (U:G) are still not fully defined. Here we have examined the ability of human SMUG1...

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Detalles Bibliográficos
Autores principales: Pettersen, Henrik Sahlin, Sundheim, Ottar, Gilljam, Karin Margaretha, Slupphaug, Geir, Krokan, Hans Einar, Kavli, Bodil
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919486/
https://www.ncbi.nlm.nih.gov/pubmed/17537817
http://dx.doi.org/10.1093/nar/gkm372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919486/
https://www.ncbi.nlm.nih.gov/pubmed/17537817
http://dx.doi.org/10.1093/nar/gkm372

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