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Cellular antisense activity of peptide nucleic acid (PNAs) targeted to HIV-1 polypurine tract (PPT) containing RNA

DNA and RNA oligomers that contain stretches of guanines can associate to form stable secondary structures including G-quadruplexes. Our study shows that the (UUAAAAGAAAAGGGGGGAU) RNA sequence, from the human immunodeficiency virus type 1 (HIV-1 polypurine tract or PPT sequence) forms in vitro a sta...

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Detalles Bibliográficos
Autores principales: Boutimah-Hamoudi, Fatima, Leforestier, Erwan, Sénamaud-Beaufort, Catherine, Nielsen, Peter E., Giovannangeli, Carine, Saison-Behmoaras, Tula Ester
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919497/
https://www.ncbi.nlm.nih.gov/pubmed/17537815
http://dx.doi.org/10.1093/nar/gkm374