A chemical synthesis of LNA-2,6-diaminopurine riboside, and the influence of 2′-O-methyl-2,6-diaminopurine and LNA-2,6-diaminopurine ribosides on the thermodynamic properties of 2′-O-methyl RNA/RNA heteroduplexes

Modified nucleotides are useful tools to study the structures, biological functions and chemical and thermodynamic stabilities of nucleic acids. Derivatives of 2,6-diaminopurine riboside (D) are one type of modified nucleotide. The presence of an additional amino group at position 2 relative to aden...

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Detalles Bibliográficos
Autores principales: Pasternak, Anna, Kierzek, Elzbieta, Pasternak, Karol, Turner, Douglas H., Kierzek, Ryszard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919511/
https://www.ncbi.nlm.nih.gov/pubmed/17567607
http://dx.doi.org/10.1093/nar/gkm421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919511/
https://www.ncbi.nlm.nih.gov/pubmed/17567607
http://dx.doi.org/10.1093/nar/gkm421

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