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Reprogramming the tRNA-splicing activity of a bacterial RNA repair enzyme

Programmed RNA breakage is an emerging theme underlying cellular responses to stress, virus infection and defense against foreign species. In many cases, site-specific cleavage of the target RNA generates 2′,3′ cyclic phosphate and 5′-OH ends. For the damage to be repaired, both broken ends must be...

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Detalles Bibliográficos
Autores principales: Keppetipola, Niroshika, Nandakumar, Jayakrishnan, Shuman, Stewart
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920235/
https://www.ncbi.nlm.nih.gov/pubmed/17488852
http://dx.doi.org/10.1093/nar/gkm110