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G-quadruplex formation in human telomeric (TTAGGG)(4) sequence with complementary strand in close vicinity under molecularly crowded condition
Chromosomes in vertebrates are protected at both ends by telomere DNA composed of tandem (TTAGGG)(n) repeats. DNA replication produces a blunt-ended leading strand telomere and a lagging strand telomere carrying a single-stranded G-rich overhang at its end. The G-rich strand can form G-quadruplex st...
Autores principales: | Kan, Zhong-yuan, Lin, Yi, Wang, Feng, Zhuang, Xin-ying, Zhao, Yong, Pang, Dai-wen, Hao, Yu-hua, Tan, Zheng |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920240/ https://www.ncbi.nlm.nih.gov/pubmed/17488850 http://dx.doi.org/10.1093/nar/gkm203 |
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