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G-quadruplex formation in human telomeric (TTAGGG)(4) sequence with complementary strand in close vicinity under molecularly crowded condition

Chromosomes in vertebrates are protected at both ends by telomere DNA composed of tandem (TTAGGG)(n) repeats. DNA replication produces a blunt-ended leading strand telomere and a lagging strand telomere carrying a single-stranded G-rich overhang at its end. The G-rich strand can form G-quadruplex st...

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Detalles Bibliográficos
Autores principales: Kan, Zhong-yuan, Lin, Yi, Wang, Feng, Zhuang, Xin-ying, Zhao, Yong, Pang, Dai-wen, Hao, Yu-hua, Tan, Zheng
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920240/
https://www.ncbi.nlm.nih.gov/pubmed/17488850
http://dx.doi.org/10.1093/nar/gkm203