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Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA
Large numbers of guanine-rich sequences with potential to form G-quadruplexes have been identified in genomes of various organisms. Such sequences are constrained at both ends by long DNA duplex with a complementary strand in close proximity to compete for duplex formation. G-quadruplex/duplex compe...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800236/ https://www.ncbi.nlm.nih.gov/pubmed/19858105 http://dx.doi.org/10.1093/nar/gkp898 |