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SNAP: predict effect of non-synonymous polymorphisms on function
Many genetic variations are single nucleotide polymorphisms (SNPs). Non-synonymous SNPs are ‘neutral’ if the resulting point-mutated protein is not functionally discernible from the wild type and ‘non-neutral’ otherwise. The ability to identify non-neutral substitutions could significantly aid targe...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920242/ https://www.ncbi.nlm.nih.gov/pubmed/17526529 http://dx.doi.org/10.1093/nar/gkm238 |