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General transfer matrix formalism to calculate DNA–protein–drug binding in gene regulation: application to O(R) operator of phage λ
The transfer matrix methodology is proposed as a systematic tool for the statistical–mechanical description of DNA–protein–drug binding involved in gene regulation. We show that a genetic system of several cis-regulatory modules is calculable using this method, considering explicitly the site-overla...
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920246/ https://www.ncbi.nlm.nih.gov/pubmed/17526526 http://dx.doi.org/10.1093/nar/gkm268 |