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Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis
Fanconi anemia (FA) is a chromosomal instability disorder in which DNA-damage processing defects are reported for translesion synthesis (TLS), non-homologous end joining (NHEJ) and homologous recombination (HR; both increased and decreased). To reconcile these diverse findings, we compared spontaneo...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920256/ https://www.ncbi.nlm.nih.gov/pubmed/17517774 http://dx.doi.org/10.1093/nar/gkm315 |