Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis

Fanconi anemia (FA) is a chromosomal instability disorder in which DNA-damage processing defects are reported for translesion synthesis (TLS), non-homologous end joining (NHEJ) and homologous recombination (HR; both increased and decreased). To reconcile these diverse findings, we compared spontaneo...

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Detalles Bibliográficos
Autores principales: Hinz, John M., Nham, Peter B., Urbin, Salustra S., Jones, Irene M., Thompson, Larry H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920256/
https://www.ncbi.nlm.nih.gov/pubmed/17517774
http://dx.doi.org/10.1093/nar/gkm315

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