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Cell cycle regulation as a mechanism for functional separation of the apparently redundant uracil DNA glycosylases TDG and UNG2

Human Thymine-DNA Glycosylase (TDG) is a member of the uracil DNA glycosylase (UDG) superfamily. It excises uracil, thymine and a number of chemical base lesions when mispaired with guanine in double-stranded DNA. These activities are not unique to TDG; at least three additional proteins with simila...

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Detalles Bibliográficos
Autores principales: Hardeland, Ulrike, Kunz, Christophe, Focke, Frauke, Szadkowski, Marta, Schär, Primo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920262/
https://www.ncbi.nlm.nih.gov/pubmed/17526518
http://dx.doi.org/10.1093/nar/gkm337