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Rapid Identification of Malaria Vaccine Candidates Based on α-Helical Coiled Coil Protein Motif

To identify malaria antigens for vaccine development, we selected α-helical coiled coil domains of proteins predicted to be present in the parasite erythrocytic stage. The corresponding synthetic peptides are expected to mimic structurally “native” epitopes. Indeed the 95 chemically synthesized pept...

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Detalles Bibliográficos
Autores principales: Villard, Viviane, Agak, George W., Frank, Géraldine, Jafarshad, Ali, Servis, Catherine, Nébié, Issa, Sirima, Sodiomon B., Felger, Ingrid, Arevalo-Herrera, Myriam, Herrera, Socrates, Heitz, Frederic, Bäcker, Volker, Druilhe, Pierre, Kajava, Andrey V., Corradin, Giampietro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920550/
https://www.ncbi.nlm.nih.gov/pubmed/17653272
http://dx.doi.org/10.1371/journal.pone.0000645