Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

BACKGROUND: CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C. In contrast, in evolving chronic hepatitis C CD4+ T cell helper responses appear to be absent or short-lived, using functional assays. METHO...

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Detalles Bibliográficos
Autores principales: Lucas, Michaela, Ulsenheimer, Axel, Pfafferot, Katja, Heeg, Malte H.J., Gaudieri, Silvana, Grüner, Norbert, Rauch, Andri, Gerlach, J. Tilman, Jung, Maria-Christina, Zachoval, Reinhart, Pape, Gerd R., Schraut, Winfried, Santantonio, Teresa, Nitschko, Hans, Obermeier, Martin, Phillips, Rodney, Scriba, Thomas J., Semmo, Nasser, Day, Cheryl, Weber, Jonathan N., Fidler, Sarah, Thimme, Robert, Haberstroh, Anita, Baumert, Thomas F., Klenerman, Paul, Diepolder, Helmut M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920556/
https://www.ncbi.nlm.nih.gov/pubmed/17653276
http://dx.doi.org/10.1371/journal.pone.0000649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920556/
https://www.ncbi.nlm.nih.gov/pubmed/17653276
http://dx.doi.org/10.1371/journal.pone.0000649

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