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Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection
BACKGROUND: CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C. In contrast, in evolving chronic hepatitis C CD4+ T cell helper responses appear to be absent or short-lived, using functional assays. METHO...
Autores principales: | Lucas, Michaela, Ulsenheimer, Axel, Pfafferot, Katja, Heeg, Malte H.J., Gaudieri, Silvana, Grüner, Norbert, Rauch, Andri, Gerlach, J. Tilman, Jung, Maria-Christina, Zachoval, Reinhart, Pape, Gerd R., Schraut, Winfried, Santantonio, Teresa, Nitschko, Hans, Obermeier, Martin, Phillips, Rodney, Scriba, Thomas J., Semmo, Nasser, Day, Cheryl, Weber, Jonathan N., Fidler, Sarah, Thimme, Robert, Haberstroh, Anita, Baumert, Thomas F., Klenerman, Paul, Diepolder, Helmut M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920556/ https://www.ncbi.nlm.nih.gov/pubmed/17653276 http://dx.doi.org/10.1371/journal.pone.0000649 |
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