Cargando…

Heterologous Amyloid Seeding: Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease

Neurodegenerative diseases associated with abnormal protein folding and ordered aggregation require an initial trigger which may be infectious, inherited, post-inflammatory or idiopathic. Proteolytic cleavage to generate vulnerable precursors, such as amyloid-β peptide (Aβ) production via β and γ se...

Descripción completa

Detalles Bibliográficos
Autores principales: Jean, Létitia, Thomas, Benjamin, Tahiri-Alaoui, Abdessamad, Shaw, Michael, Vaux, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920558/
https://www.ncbi.nlm.nih.gov/pubmed/17653279
http://dx.doi.org/10.1371/journal.pone.0000652