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Histidine Triad-like Motif of the Rotavirus NSP2 Octamer Mediates both RTPase and NTPase Activities

Rotavirus NSP2 is an abundant non-structural RNA-binding protein essential for forming the viral factories that support replication of the double-stranded RNA genome. NSP2 exists as stable doughnut-shaped octamers within the infected cell, representing the tail-to-tail interaction of two tetramers....

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Detalles Bibliográficos
Autores principales: Vasquez-Del Carpio, Rodrigo, Gonzalez-Nilo, Fernando D., Riadi, Gonzalo, Taraporewala, Zenobia F., Patton, John T.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1924841/
https://www.ncbi.nlm.nih.gov/pubmed/16934294
http://dx.doi.org/10.1016/j.jmb.2006.07.050