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Computationally Derived Points of Fragility of a Human Cascade Are Consistent with Current Therapeutic Strategies

The role that mechanistic mathematical modeling and systems biology will play in molecular medicine and clinical development remains uncertain. In this study, mathematical modeling and sensitivity analysis were used to explore the working hypothesis that mechanistic models of human cascades, despite...

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Detalles Bibliográficos
Autores principales: Luan, Deyan, Zai, Michael, Varner, Jeffrey D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1924874/
https://www.ncbi.nlm.nih.gov/pubmed/17658944
http://dx.doi.org/10.1371/journal.pcbi.0030142