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Non-linear dimensionality reduction of signaling networks
BACKGROUND: Systems wide modeling and analysis of signaling networks is essential for understanding complex cellular behaviors, such as the biphasic responses to different combinations of cytokines and growth factors. For example, tumor necrosis factor (TNF) can act as a proapoptotic or prosurvival...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925119/ https://www.ncbi.nlm.nih.gov/pubmed/17559646 http://dx.doi.org/10.1186/1752-0509-1-27 |