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Non-linear dimensionality reduction of signaling networks

BACKGROUND: Systems wide modeling and analysis of signaling networks is essential for understanding complex cellular behaviors, such as the biphasic responses to different combinations of cytokines and growth factors. For example, tumor necrosis factor (TNF) can act as a proapoptotic or prosurvival...

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Detalles Bibliográficos
Autores principales: Ivakhno, Sergii, Armstrong, J Douglas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925119/
https://www.ncbi.nlm.nih.gov/pubmed/17559646
http://dx.doi.org/10.1186/1752-0509-1-27