Cargando…

Relationship between insertion/deletion (indel) frequency of proteins and essentiality

BACKGROUND: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human proteins of high sequence similarity. Such indels may provide sufficient spatial differences between the pathogenic protein an...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Simon K, Hsing, Michael, Hormozdiari, Fereydoun, Cherkasov, Artem
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925122/
https://www.ncbi.nlm.nih.gov/pubmed/17598914
http://dx.doi.org/10.1186/1471-2105-8-227