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Relationship between insertion/deletion (indel) frequency of proteins and essentiality
BACKGROUND: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human proteins of high sequence similarity. Such indels may provide sufficient spatial differences between the pathogenic protein an...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925122/ https://www.ncbi.nlm.nih.gov/pubmed/17598914 http://dx.doi.org/10.1186/1471-2105-8-227 |