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Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

Several vertebrate microRNAs (miRNAs) have been implicated in cellular processes such as muscle differentiation, synapse function, and insulin secretion. In addition, analysis of Dicer null mutants has shown that miRNAs play a role in tissue morphogenesis. Nonetheless, only a few loss-of-function ph...

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Detalles Bibliográficos
Autores principales: Kloosterman, Wigard P, Lagendijk, Anne K, Ketting, René F, Moulton, Jon D, Plasterk, Ronald H. A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925136/
https://www.ncbi.nlm.nih.gov/pubmed/17676975
http://dx.doi.org/10.1371/journal.pbio.0050203