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Cathepsin K Null Mice Show Reduced Adiposity during the Rapid Accumulation of Fat Stores

Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white adipose tissue (WAT) of obese individuals. We herein characterized the WAT and the metabolic phenot...

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Detalles Bibliográficos
Autores principales: Funicello, Marcella, Novelli, Michela, Ragni, Maurizio, Vottari, Teresa, Cocuzza, Cesare, Soriano-Lopez, Joaquin, Chiellini, Chiara, Boschi, Federico, Marzola, Pasquina, Masiello, Pellegrino, Saftig, Paul, Santini, Ferruccio, St-Jacques, Rene, Desmarais, Sylvie, Morin, Nicolas, Mancini, Joseph, Percival, M. David, Pinchera, Aldo, Maffei, Margherita
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925145/
https://www.ncbi.nlm.nih.gov/pubmed/17668061
http://dx.doi.org/10.1371/journal.pone.0000683