Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia

BACKGROUND: The Na(+), K(+), 2Cl(- )type I cotransporter (NKCC1) and TRPV1 receptors, at the level of the dorsal horn, have been implicated in mediating allodynia in response to an inflammatory insult. The NKCC1 cotransporter regulates intracellular [Cl(-)] and thus the magnitude and polarity of GAB...

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Detalles Bibliográficos
Autores principales: Pitcher, Mark H, Price, Theodore J, Entrena, Jose M, Cervero, Fernando
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929059/
https://www.ncbi.nlm.nih.gov/pubmed/17603899
http://dx.doi.org/10.1186/1744-8069-3-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929059/
https://www.ncbi.nlm.nih.gov/pubmed/17603899
http://dx.doi.org/10.1186/1744-8069-3-17

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