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Drotrecogin alfa (activated) in severe sepsis: a systematic review and new cost-effectiveness analysis
BACKGROUND: Activated drotrecogin alfa (human activated protein C, rhAPC), is produced by recombinant DNA technology, and purports to improve clinical outcomes by counteracting the inflammatory and thrombotic consequences of severe sepsis. Controversy exists around the clinical benefits of this drug...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929064/ https://www.ncbi.nlm.nih.gov/pubmed/17592639 http://dx.doi.org/10.1186/1471-2253-7-5 |