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A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina

BACKGROUND: Otx genes, orthologues of the Drosophila orthodenticle gene (otd), play crucial roles in vertebrate brain development. In the Xenopus eye, Xotx2 and Xotx5b promote bipolar and photoreceptor cell fates, respectively. The molecular basis of their differential action is not completely under...

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Detalles Bibliográficos
Autores principales: Onorati, Marco, Cremisi, Federico, Liu, Yang, He, Rong-Qiao, Barsacchi, Giuseppina, Vignali, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929070/
https://www.ncbi.nlm.nih.gov/pubmed/17597530
http://dx.doi.org/10.1186/1749-8104-2-12