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HER2 gene status in primary breast cancers and matched distant metastases

INTRODUCTION: The status of the gene encoding human EGF-like receptor 2 (HER2) is an important prognostic and predictive marker in breast cancer. Only breast cancers with HER2 amplification respond to the targeted therapy with trastuzumab. It is controversial to what degree the primary tumour is rep...

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Detalles Bibliográficos
Autores principales: Tapia, Coya, Savic, Spasenija, Wagner, Urs, Schönegg, René, Novotny, Hedvika, Grilli, Bruno, Herzog, Michelle, Barascud, Audrey DeVito, Zlobec, Inti, Cathomas, Gieri, Terracciano, Luigi, Feichter, Georg, Bubendorf, Lukas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929093/
https://www.ncbi.nlm.nih.gov/pubmed/17511881
http://dx.doi.org/10.1186/bcr1676