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An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells
INTRODUCTION: About 70% of breast cancers express oestrogen receptor α (ESR1/ERα) and are oestrogen-dependent for growth. In contrast with the highly proliferative nature of ERα-positive tumour cells, ERα-positive cells in normal breast tissue rarely proliferate. Because ERα expression is rapidly lo...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929103/ https://www.ncbi.nlm.nih.gov/pubmed/17573968 http://dx.doi.org/10.1186/bcr1734 |