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External Contamination in Single Cell mtDNA Analysis

BACKGROUND: Mitochondrial DNA (mtDNA) variation in single hematopoietic cells, muscle fibers, oocytes, and from tiny amount of tumor tissues and degraded clinical specimens has been reported in many medical publications. External DNA contamination, notoriously difficult to avoid, threatens the integ...

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Detalles Bibliográficos
Autores principales: Yao, Yong-Gang, Bandelt, Hans-Jürgen, Young, Neal S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1930155/
https://www.ncbi.nlm.nih.gov/pubmed/17668059
http://dx.doi.org/10.1371/journal.pone.0000681