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Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets

BACKGROUND: MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation. MECP2 mutations in females lead to Rett syndrome, a neurological disorder characterized by developmental stagnation and regression,...

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Detalles Bibliográficos
Autores principales: Jordan, ChaRandle, Li, Hong Hua, Kwan, Helen C, Francke, Uta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931432/
https://www.ncbi.nlm.nih.gov/pubmed/17584923
http://dx.doi.org/10.1186/1471-2350-8-36