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Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets
BACKGROUND: MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation. MECP2 mutations in females lead to Rett syndrome, a neurological disorder characterized by developmental stagnation and regression,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931432/ https://www.ncbi.nlm.nih.gov/pubmed/17584923 http://dx.doi.org/10.1186/1471-2350-8-36 |