Enhancement of intracellular γ-tocopherol levels in cytokine-stimulated C3H 10T1/2 fibroblasts: relation to NO synthesis, isoprostane formation, and tocopherol oxidation

BACKGROUND: Stimulation of C3H 10T1/2 murine fibroblasts with interferon-γ(IFN) and bacterial lipopolysaccharide (LPS) generates reactive oxygen and nitrogen species leading to DNA damage, lipid oxidation, and tocopherol oxidation. The tocopherols possess unique chemical and biological properties th...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuichiro, Wood, Leslie A Lesoon, Cooney, Robert V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931582/
https://www.ncbi.nlm.nih.gov/pubmed/17608946
http://dx.doi.org/10.1186/1472-6769-7-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931582/
https://www.ncbi.nlm.nih.gov/pubmed/17608946
http://dx.doi.org/10.1186/1472-6769-7-2

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