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Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO

BACKGROUND: The rational design of peptide-based specific inhibitors of the caspase family members using their X-ray crystallographies is an important strategy for chemical knockdown to define the critical role of each enzyme in apoptosis and inflammation. Recently, we designed a novel potent peptid...

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Detalles Bibliográficos
Autores principales: Yoshimori, Atsushi, Sakai, Junichi, Sunaga, Satoshi, Kobayashi, Takanobu, Takahashi, Satoshi, Okita, Naoyuki, Takasawa, Ryoko, Tanuma, Sei-ichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931592/
https://www.ncbi.nlm.nih.gov/pubmed/17594508
http://dx.doi.org/10.1186/1471-2210-7-8