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Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO
BACKGROUND: The rational design of peptide-based specific inhibitors of the caspase family members using their X-ray crystallographies is an important strategy for chemical knockdown to define the critical role of each enzyme in apoptosis and inflammation. Recently, we designed a novel potent peptid...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931592/ https://www.ncbi.nlm.nih.gov/pubmed/17594508 http://dx.doi.org/10.1186/1471-2210-7-8 |