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Using biomarker signature patterns for an mRNA molecular diagnostic of mouse embryonic stem cell differentiation state

BACKGROUND: The pluripotency and self-renewal capabilities, which define the "stemness" state, of mouse embryonic stem (ES) cells, are usually investigated by functional assays or quantitative measurements of the expression levels of known ES cell markers. Strong correlations between these...

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Detalles Bibliográficos
Autores principales: Yap, Daniel YL, Smith, David K, Zhang, Xue W, Hill, Jeffrey
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931595/
https://www.ncbi.nlm.nih.gov/pubmed/17605829
http://dx.doi.org/10.1186/1471-2164-8-210