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Enhanced effect of microdystrophin gene transfection by HSV-VP22 mediated intercellular protein transport
BACKGROUND: Duchenne musclar dystrophy (DMD) is an X-linked recessive disease caused by mutations of dystrophin gene, there is no effective treatment for this disorder at present. Plasmid-mediated gene therapy is a promising therapeutical approach for the treatment of DMD. One of the major issues wi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931604/ https://www.ncbi.nlm.nih.gov/pubmed/17617925 http://dx.doi.org/10.1186/1471-2202-8-50 |