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Enhanced effect of microdystrophin gene transfection by HSV-VP22 mediated intercellular protein transport

BACKGROUND: Duchenne musclar dystrophy (DMD) is an X-linked recessive disease caused by mutations of dystrophin gene, there is no effective treatment for this disorder at present. Plasmid-mediated gene therapy is a promising therapeutical approach for the treatment of DMD. One of the major issues wi...

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Detalles Bibliográficos
Autores principales: Xiong, Fu, Xiao, Shaobo, Yu, Meijuan, Li, Wanyi, Zheng, Hui, Shang, Yanchang, Peng, Funing, Zhao, Cuiping, Zhou, Wenliang, Chen, Huanchun, Fang, Liurong, Chamberlain, Jeffrey S, Zhang, Cheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931604/
https://www.ncbi.nlm.nih.gov/pubmed/17617925
http://dx.doi.org/10.1186/1471-2202-8-50