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RF-DYMHC: detecting the yeast meiotic recombination hotspots and coldspots by random forest model using gapped dinucleotide composition features

In the yeast, meiotic recombination is initiated by double-strand DNA breaks (DSBs) which occur at relatively high frequencies in some genomic regions (hotspots) and relatively low frequencies in others (coldspots). Although observations concerning individual hot/cold spots have given clues as to th...

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Detalles Bibliográficos
Autores principales: Jiang, Peng, Wu, Haonan, Wei, Jiawei, Sang, Fei, Sun, Xiao, Lu, Zuhong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933199/
https://www.ncbi.nlm.nih.gov/pubmed/17478517
http://dx.doi.org/10.1093/nar/gkm217