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Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells

BACKGROUND: A major obstacle for successful cancer treatment often is the development of drug resistance in cancer cells during chemotherapy. Therefore, there is an urgent need for novel drugs with improved efficacy against tumor cells and with less toxicity on normal cells. Artesunate (ART), a powe...

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Detalles Bibliográficos
Autores principales: Efferth, Thomas, Giaisi, Marco, Merling, Annette, Krammer, Peter H., Li-Weber, Min
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933253/
https://www.ncbi.nlm.nih.gov/pubmed/17668070
http://dx.doi.org/10.1371/journal.pone.0000693