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Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells
BACKGROUND: A major obstacle for successful cancer treatment often is the development of drug resistance in cancer cells during chemotherapy. Therefore, there is an urgent need for novel drugs with improved efficacy against tumor cells and with less toxicity on normal cells. Artesunate (ART), a powe...
Autores principales: | Efferth, Thomas, Giaisi, Marco, Merling, Annette, Krammer, Peter H., Li-Weber, Min |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933253/ https://www.ncbi.nlm.nih.gov/pubmed/17668070 http://dx.doi.org/10.1371/journal.pone.0000693 |
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