Generation of human scFvs antibodies recognizing a prion protein epitope expressed on the surface of human lymphoblastoid cells

BACKGROUND: A hallmark of prion disease is the transformation of normal cellular prion protein (PrPc) into an infectious disease-associated isoform, (PrPsc). Anti-prion protein monoclonal antibodies are invaluable for structure-function studies of PrP molecules. Furthermore recent in vitro and in vi...

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Detalles Bibliográficos
Autores principales: Flego, Michela, Ascione, Alessandro, Zamboni, Silvia, Dupuis, Maria L, Imperiale, Valentina, Cianfriglia, Maurizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933425/
https://www.ncbi.nlm.nih.gov/pubmed/17605808
http://dx.doi.org/10.1186/1472-6750-7-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933425/
https://www.ncbi.nlm.nih.gov/pubmed/17605808
http://dx.doi.org/10.1186/1472-6750-7-38

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