Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms

Interferon regulatory factor (IRF)-3 is a master transcription factor that activates host antiviral defense programs. Although cell culture studies suggest that IRF-3 promotes antiviral control by inducing interferon (IFN)-β, near normal levels of IFN-α and IFN-β were observed in IRF-3(−/−) mice aft...

Descripción completa

Detalles Bibliográficos
Autores principales: Daffis, Stephane, Samuel, Melanie A, Keller, Brian C, Gale, Michael, Diamond, Michael S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933455/
https://www.ncbi.nlm.nih.gov/pubmed/17676997
http://dx.doi.org/10.1371/journal.ppat.0030106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933455/
https://www.ncbi.nlm.nih.gov/pubmed/17676997
http://dx.doi.org/10.1371/journal.ppat.0030106

Ejemplares similares